Antonelli M, Penfold RS, Merino J, Sudre CH, Molteni E, Berry S, Canas LS, Graham MS, Klaser K, Modat M, Murray B, Kerfoot E, Chen L, Deng J, Österdahl MF, Cheetham NJ, Drew DA, Nguyen LH, Pujol JC, Hu C, Selvachandran S, Polidori L, May A, Wolf J, Chan AT, Hammers A, Duncan EL, Spector TD, Ourselin S, Steves CJ. Trends in Geographic and Temporal Distribution of US Children With Multisystem Inflammatory Syndrome During the COVID-19 Pandemic.
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In order to prevent the increasing number of cases of MIS-C as well as the long covid-19 and complications it causes in children, it is necessary to vaccinate the society as soon as possible and implement vaccinations both among teenagers and children below 12 years old to protect the youngest from complications and hospitalization.ġ. (3) With the SARS-CoV-2 delta variant and the fact that, according to CDC reports, the greatest infectivity affects children, prevention in the form of only recommended masks may not be sufficient, especially since, apart from children's stay in the rooms, they have constant contact with each other outside classes where the virus can be very harmful. (2) the trend shows that among vaccinated people symptoms lasting more than 4 weeks are reduced by about 50%, studies show that only 0.2% of vaccinated people developed symptoms Covid-19 and of the 592 people (still followed for a month), only 5% developed long Covid 19, while in the unvaccinated group this percentage was twice as high (11%). In some cases, children who get Covid-19 mildly or even asymptomatically end up in the hospital weeks or months later with a condition called PIMS- The CDC said at least 4,404 cases of PIMS were reported between February 2020 and July 2021. Almost half (46.4% of children hospitalized between March 2020 and June 2021) had the disease asymptomatically and long-Covid-19 can occur in children who initially had mild symptoms or were asymptomatic. This is of great concern due to the percentage of patients and the number of places in pediatric wards (remember that there are much fewer pediatric beds available than those in adult wards). With such a high number of infections in children as never before, complications will never occur more often in this MIS-C. According to the latest CDC morbidity data and a report from the American Academy of Pediatrics for children about 200,000 new cases of Covid-19 in children were reported in the week ending August 26, which is a 5-fold increase in a month and the percentage of hospitalizations was 330 children per day (half of whom are under 2 years of age).
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(1) rightly point out, the geographical and temporal link between MIS-C and the COVID-19 pandemic suggests that MIS-C is the result of delayed immune responses to SARS-CoV-2 infection, but in the current pandemic situation, the geographical distribution of MIS-C may be changed to mainly in terms of the worst-vaccinated regions of the country.
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